Wow - The Browns are missing both their primary and backup RBs in Nick Chubb and Kareem Hunt, their starting QB Baker Mayfield, their starting left and right tackles, and slot WR Jarvis Landry, with Odell Beckham being unlikely to suit up as well. That leaves Case Keenum to drive what's left of this offense against a strong Broncos defense.
D'Ernest Johnson - Johnson figures to see the ball often in his first NFL start with injuries decimating the QB room and the WR corps. Johnson has 40 career carries for almost 5 YPC, and 10 catches for 92 yards. With 6 teams on bye this week, and the number of injuries to the position, Johnson is an RB2 play this week with a safe floor in a game where he should see 20 touches.
Browns D/ST - The secondary is battling injuries on their side of the ball as well, but their pass rush is one of the most effective in the league with Myles Garrett and Jadeveon Clowney. Denver has had problems protecting the QB this year allowing at least two sacks per game, and Denver has turned the ball over at least once in 5 of their 6 games.
Case Keenum - Keenum doesn't have a lot of offensive weapons at his disposal in this one with TEs David Njoku and Austin Hooper being his most reliable options. The Browns figure to run the ball often in this one, and Keenum shouldn't be used unless your team is in the most dire of circumstances in a two QB league.
Austin Hooper and David Njoku - As noted, these are the top options not to be on the injury report for tonight's contest. The Broncos are second best in the league against opposing TEs, and their inconsistency week to week makes it difficult to count on either option, as they've averaged 3 targets each through 6 weeks. If you need to start one, Njoku has the best upside, but shouldn't be viewed as more than an emergency play at best.
Donovan Peoples-Jones and Rashard Higgins - These are the top healthy WRs for Case Keenum tonight. Peoples-Jones had a big week last week catching 4 catches for 101 yards and a pair of scores, but his 4 catches and 101 yards nearly doubled his production from the first 5 weeks. Higgins has 11 catches for 143 yards on the season. Neither should be viewed as more than an emergency WR3 either.
Demetric Felton - Felton figures to operate in the Kareem Hunt pass catching role, but has yet to log his first NFL carry, and only has 8 catches so far this year. Felton shouldn't be viewed as anything more than a worst case scenario play either this week. You have better options.
Teddy Bridgewater - Although listed as questionable, Bridgewater should start tonight's game. Cleveland has allowed multiple passing TDs in 4 of their 6 games this year, and the other two were Justin Fields' first start, and a Minnesota Vikings team that put up 7 points. Teddy has multiple passing scores in 4 of his 6 games this year as well, and topped 300 yards twice including last week against the Raiders, despite 4 turnovers. Bridgewater is a safe streamer this week.
Courtland Sutton - If we like Bridgewater, we also probably like a few of his pass catchers. Sutton is coming off a big week 6 game that saw him catch 7+ balls for this third time this year, and score for the second week in a row. Sutton has 53 targets in 6 games that should give him a safe floor, and a high upside against a Browns D that has been stingy against the run. Start him as a low WR1 or high end WR2 with confidence.
Tim Patrick - As of the time of this writing, Jerry Jeudy is no more than 50/50 to come off IR before tonight's contest. Patrick has seen no fewer than 5 targets in each of his last 4 games, and has scored or logged 89+ yards in three of those. Patrick can be viewed as a safe floor WR2/3 play this week if Jeudy misses another game.
Noah Fant - Fant is also coming off a strong week 6 against the Raiders that saw him catch a season high 9 passes for 97 yards and a score, along with a 22% target share. With an average 7 targets a game, Fant is will be a locked in TE1 once again.
Melvin Gordon and Javonte Williams - Both RBs seem to be locked in a never ending time share, and that doesn't figure to end this week. Cleveland has a strong rush defense, but Denver figures to be up and running often in the second half. Both of these RBs can be viewed as RB2/Flex in this one.
Denver D/ST - With the number of injuries to the Cleveland offense, this defense should have ample opportunities against inexperience options and a backup QB.